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ExEm® Foam is a highly echogenic medium and offers an exceptional visualization of the fallopian tubes. Moreover, studies confirm that, using the right imaging techniques, the accuracy of a HyFoSy procedure using ExEm® Foam does not significantly differ from what you achieve through laparoscopy. The same studies demonstrate that HyFoSy has the ability to achieve significantly higher accuracy than 2D saline and air1.
ExEm® Foam intrauterine foam images of the uterus with the Fallopian tubes in two women with known or suspected infertility.
In one patient, both tubes showed patency (left column), and in the other patient, the left tube was occluded and the right one was patent (right column, confirmed by the reference standard). (A) and (B) 2D-HyFoSy, (C) and (D) offline HD-live rendered 3D-HyFoSy, (E) and (F) 2D-HDF-HyFoSy and (G) and (H) offline color-rendered 3D-HDF-HyFoSy showing the same diagnosis as the reference standard
Images (E) through (F): if the foam flow is present throughout the catheter, the uterus, and the patent tube during infusion, positive contrasting by the foam is significantly enhanced by color (left column). One fallopian tube is occluded in the right column: in (B) and (D), it is partially contrasted by foam, and in (F) and (H), it is not contrasted by color.
(Source: Ludwin I, et al. 2017).
Value of the HyFoSy procedure
ExEm® Foam is a medium made of ExEm® Gel – hydroxyethyl cellulose & glycerol and ExEm® Water – purified water. When vigorously mixed, a highly echogenic foam containing 127,000 micro-air bubbles per ml is formed and can easily be seen by a qualified sonographer using 2D or 3D transvaginal ultrasound techniques.
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